Overcome skin resistance to medical topical agents by limiting their use. Skin can acquire tolerance and resistance to many topical agents, leading to treatment failure and complications. Medical topical products (e.g. hydroquinone, retinoic acid) are recommended to be used short-term for therapeutic treatment of skin conditions. Upon completion of therapeutic treatment, patients should switch to a maintenance program which includes products designed to keep skin stabilized and maintain long-term results. This approach optimizes results, limits complexions and prevents resistance. 



Retinoic Acid

Hydroquinone is essential to the treatment of many skin pigmentation disorders; however, it should not be used continuously.

Retinoic acid has profoundly beneficial effects on the skin; however, it is not recommended to continuous, long-term use. 

*Taken from page 22 from ZO Principles of Skin Health Restoration